Bloody mess is a lot of fun to play, satisfies me for a while when bored. Nothing better than seeing a raider's brains go everywhere!

I believe its was called cowboy or something similar, the one that let you fire cowboy weapons much faster, it paired nicely with lucky and hitman's fanning animations, I used that for my john Marston playthrough

Hand loader because i love the ammo types you can craft.

My favourite was Meltdown, which causes your foes to emit a corona of energy. This greatly enhances the use of energy weapons for me.

My favorite perk in fallout new vegas is Entomologist, because it is a very useful feature for Mojave wasteland overrun by mutated animals and creatures

in vanilla probally jury rigging. its just so helpful and its always my choice when i reach 14

Currently my favorite is "and stay back" if you combine it with shotgun surgeon you can become insanely overpowered.

My favorite Perk is Long Haul. I really hate not being able to fast travel while being over encumbered, and having to walk is so slow and takes way to long. It really is a pain so having Long Haul really makes me happy.